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Index > Protein center > Rgs3(Gene name) > Rat
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  • Rgs3 (Gene name),
  • Regulator of G-protein signaling 3 (Protein name ),  RGS3_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Rgs3;
    Protein name:
    Regulator of G-protein signaling 3(RGS3);
    Alternative:
    SRB-RGS;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Binds EFNB1 and EFNB2. Binds the GNB1-GNG2 heterodimer (By similarity). Binds ESR1.
    Function:
    Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.
    Subcellular Location:
    Cytoplasm Membrane Peripheral membrane protein Nucleus
    Protein Attributes:
    Sequence length:
    967
    Sequence:
    50:
    MNRFNGLCKV | CSERRYRQIT | IRRGKDGFGF | TICCDSPVRV | QAVDSGGPAE | 
    100:
    RAGLQQLDTV | LQLNERPVEH | WKCVELAHEI | RSCPSEIILL | VWRVVPQIKP | 
    150:
    GPDGGVLRRA | SCKSTHDLLS | PPNKREKNCT | HGAPTRPEQR | HSCHLVCDSS | 
    200:
    DGLLLGGWER | YTEVGKRSGQ | HTLPALSRAT | TPTDPNYIIL | APLNPGSQLL | 
    250:
    RPVYQEDAIP | EEPGTTTKGK | SYTGLGKKSR | LMKTVQTMKG | HSNYQDCSAL | 
    300:
    RPHIPHSSYG | TYVTLAPKVL | VFPVFVQPLD | LCNPARTLLL | SEELLLYEGR | 
    350:
    NKTSQVTLFA | YSDLLLFTKE | EEPGRCDVLR | NPLYLQSVKL | QEGSSEDLKF | 
    400:
    CVLYLAEKAE | CLFTLEAHSQ | EQKKRVCWCL | SENIAKQQQL | AATPTERKMF | 
    450:
    ETEADEKEMP | LVEGKGPGAE | ERTPSKDPSP | SQELPPGQEL | PPSKDPSPSQ | 
    500:
    ELPPGQELPP | SKDPSPSQEL | PPGQELPSSK | NPSPSQELPA | GQDLPPRKES | 
    550:
    FSGQEAAPGP | ESPSSEDIAT | CQNPPQSPET | STSKDSPPGQ | GSSPTTEVPS | 
    600:
    CQGLPAGQES | TSQDPLLSQE | PPAIPESSAS | DQNVLPSQES | PPSQGSLSEK | 
    650:
    ALAEQTISPG | ELPAATAGEP | SASRPNFVIP | EVRLDSAYSQ | QDGAHGGSSG | 
    700:
    EDEDAEEGEE | GEEGEEDEED | DTNDDNYGDR | NEAKRSSLIE | TGQGAEGGLS | 
    750:
    LRVQNSLRRR | THSEGSLLQE | ARGPCFASDT | TLHCSDGEGT | TSTWAIPSPR | 
    800:
    TLKKELGRNG | GSMHHLSLFF | TGHRKMSGTD | LADDVEASRK | RKSKNIAKDM | 
    850:
    KNKLAIFRRR | NESPGAQPAG | KADKTTKSFK | PTSEEALKWS | ESLEKLLLHK | 
    900:
    YGLEVFQAFL | RTEFSEENLE | FWLACEDFKK | VKSQSKMAAK | AKKIFAEFIA | 
    950:
    IQACKEVNLD | SYTREHTKEN | LQSITRGCFD | LAQKRIFGLM | EKDSYPRFLR | 
    967:
    SDLYLDLINQ | KKMSPPL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat RGS3
    Cat.:
    E0251m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat RGS3
    Cat.:
    E0251h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat RGS3
    Cat.:
    E0251r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat RGS3
    Cat.:
    U0251h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat RGS3
    Cat.:
    U0251r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat RGS3
    Cat.:
    U0251m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat RGS3
    Cat.:
    P0251Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat RGS3
    Cat.:
    P0251Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat RGS3
    Cat.:
    P0251Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat RGS3
    Monoclonal Antibody for Rat RGS3
    Monoclonal Antibody for Rat RGS3
    Protein for Rat RGS3
    Protein for Rat RGS3
    Protein for Rat RGS3

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    Linearity
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    References
    1. 1.
      "Molecular cloning and characterization of a steroid receptor-binding regulator of G-protein signaling protein cDNA."
      Ikeda M. , Hirokawa M. , Satani N. , Kinoshita T. , Watanabe Y. , Inoue H. , Tone S. , Ishikawa T. , Minatogawa Y.
      Gene273:207-214(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH ESR1;TISSUE SPECIFICITY
      tissue: Ovary.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Heart.
    3. 3.
      "EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins."
      Koelle M.R. , Horvitz H.R.
      Cell84:115-125(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 873-939 (ISOFORM 1);TISSUE SPECIFICITY
      tissue: Brain.
    4. 4.
      "Natriuretic peptides inhibit G protein activation. Mediation through cross-talk between cyclic GMP-dependent protein kinase and regulators of G protein-signaling proteins."
      Pedram A. , Razandi M. , Kehrl J. , Levin E.R.
      J. Biol. Chem.275:7365-7372(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION
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